Biolume

Niacinamide 20% - Vitamin B3
Repairs barrier function - reducing associated sensitivity, redness and irritation
Potent anti-inflammatory
Inhibits Melanosome transfer to Keratinocyte - normalising hyperpigmentation
Regulates moisture levels - over sebaceous activity slowed whilst hydration levels restored

Tetrapeptide 30 5% - Biomimetic (Skin Identical) Amino Acid Sequence
Proline - Lysine - Glutamic Acid - Lysine
Visibly diminishes hyperchromatic spots
Brightens and improves eveness of skin tone
Reduces acne lesions
Alleviates vertical and horizontally formed pigment, suitable for melasma
Safely inhibits pigmentation process without toxicity or rebound effect

Beta-White™ - Advanced Lightening Agent
Biomimetic Peptide TGF-B / Transforming Growth Factor-Beta
First ingredient with an inhibitory action on MITF (Microphtalmia - Transcription Factor)
Reducing MITF activity via cellular pathway as well as Tyrosinase reduces Melanin
B-White binds to TGF-8 receptor on Melanocytes which introduces intracellular cascade leading to reduction is MITF activity
Modulates natural skin colour and and facultative (UV infuced) pigment
Traditional lightening methods address Tyrosinase only
Liposomal encapsulation stablises and delivers Oligopeptide-68

Acetyl Tetrapeptide-2 - Biomimetic Peptide (EGCG-Epigallocatechin-3-Gallate)
Active constituent of Green Tea - initiates NRF-2 (master switch antioxidant signalling)
Shields DNA, membrane integrity and skin structure
Inhibits melanogenesis, glycation, lipid peroxidisation and oxidative stress

L-Glutathione - Master Antioxidant Tripeptide
Cysteine - Glycine - Glutamic Acid
Prevents oxidative damage and its many biological functions by binding to oxidative
compounds that damage cell membranes, DNA and energy production
Protects mitochondria (power plant of cell) to reduce apoptosis
Inhibits NF-k, the master controller of inflammation; reducing acne, psoriasis, wrinkles, melasma and age-related skin conditions
Neutralises a wide range of oxidants including superoxide, nitric oxide, carbon radicals, hydroperoxides, peroxynitrites and lipid peroxides
Strengthens immune function

Super-Ox C™ - Terminalia Ferdinandiana (Kakadu Plum)
Water soluble, extracted from superfruit Kakadu Plum, richest source of Vit. C
Free radical scavenger due to high Vit. C + Polyphenol content
Stimuates Pro-Collagen I and Hyaluronic Acid synthesis
Boosts skin radiance and luminosity

N-Acetyl Glucosamine (D) - Amino Monosaccharide
Developed as a pigment-brightening cosmeceutical
Decreases melanin production by inhibiting tyrosinase glycosylation

Beta Glucan - Polysaccharide (Complex Sugar)
Skin-soothing antioxidant
Naturally derived from oats, yeast, fungi or seaweed
Intense humectant
Boosts skin barrier and reduces redness

Microcitrus Australasica Fruit Extract - Australian Caviar/Finger Lime
Activates TRPV3 (Transcient Receptor Potential Vanilloid-3) channels located on keratinocytes and are involved in natural process of desquamation
Stimulates cell differentiation and initiates desquamation process
The calcium gradient that fosters epidermal turnover is lost in ageing process

Milk Thistle (Silymarin)
Extracted using Biomimicry technology so phyto-actives maintain full potency
Includes fatty acids including Linoleic Acid
Includes complex mixture of polyphenolic molecules including 7 flavonolignans
Reduces harmful effects of radiation, oxidative stress, inflammation, immune responses and DNA damage

Glycyrrhetinic Acid
Anti-inflammatory and Anti-bacterial
Inhibits intercellular gapjunctional communication that encourages melanin synthesis

Hyaluronic Acid - Mid-High Molecular Weight
Increases moisture retention, providing a hydrated and supple skin texture
Natural Moisturising Factor that binds x1000 it’s own weight in water
Plumps surface tissue to alleviate dry, thinning and scaly skin
Assists wound healing and repairs barrier function
Inhibits Trans Epidermal Water Loss - essential for atopic and dehydrated skins

Hyaluronic Acid - Low Molecular Weight
Penetrates effectively to rebuild and plump deeper layers
Biological activity triggers built-in immune defence mechanisms whilst inducing anti-bacterial responses
Trials indicate reduction in immune-derived inflammation; improving scaling, erythema and pruritus

Coenzyme Q10
Plays essential role in biological machinery, producing biological energy (ATP) inside cells, aiding repair and keeping cells healthy
Potent antioxidant, neutralises harmful free radicals

Resveratrol
Potent phytoalexin antioxidant found in red grapes and knot weed
Protects against UV radiation and DNA damage
Anti-inflammatory, anti-bacterial, natural phytoestrogen, anti-acne
Natural phytoestrogen calms, suppresses blemishes and balances sebum

Seabuckthorn CO2 Oil
Potent anti-inflammatory containing omegas 3+6
Contains Vitamins A + E

Mangosteen Peel Extract
Antioxidant, neutralises oxidative damage
Reduces collagen, elastin and hyaluronic acid-degrading enzymes

Apple Fruit Extract
Polyphenolic Antioxidant
Skin-smoothing

Can be applied up to x2 daily as serum or spot treatment step
Can be applied all over daily 2 weeks Pre Rx to inhibit PIHP formation